Solute carrier family 9 member D1 (SLC9D1)
Homo sapiens — UniProt Q6UWJ1
Data last refreshed: (UniProt release unknown)
Key facts
Solute carrier family 9 member D1 (SLC9D1) is a protein from Homo sapiens identified by UniProt accession Q6UWJ1, 677 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q6UWJ1; gene symbol SLC9D1.
- Organism: Homo sapiens.
- Length: 677 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, neutrophil count and leukocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Solute carrier family 9 member D1 |
|---|---|
| UniProt accession | Q6UWJ1 |
| Gene | SLC9D1 |
| Organism | Homo sapiens |
| Length | 677 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- neutrophil count · score 0.38
- leukocyte count · score 0.37
- neutrophil percentage of leukocytes · score 0.33
- myeloid white cell count · score 0.31
- electrocardiography · score 0.29
- reticulocyte count · score 0.29
- mean reticulocyte volume · score 0.26
- mean corpuscular volume · score 0.25
- monocyte percentage of leukocytes · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWJ1-F1 | alphafold | PREDICTED | 75.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWJ1.
Amino-acid sequence (677 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC9D1?
The strongest Open Targets associations for SLC9D1 are neurodegenerative disease, neutrophil count, leukocyte count, neutrophil percentage of leukocytes and myeloid white cell count.
How long is the SLC9D1 protein?
The Homo sapiens SLC9D1 protein (UniProt Q6UWJ1) is 677 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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