Protein GPR15LG (GPR15LG)
Homo sapiens — UniProt Q6UWK7
Data last refreshed: (UniProt release unknown)
Key facts
Protein GPR15LG (GPR15LG) is a protein from Homo sapiens identified by UniProt accession Q6UWK7, 81 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q6UWK7; gene symbol GPR15LG.
- Organism: Homo sapiens.
- Length: 81 amino acids.
- Top disease associations (Open Targets): influenza A (H1N1), psoriasis and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein GPR15LG |
|---|---|
| UniProt accession | Q6UWK7 |
| Gene | GPR15LG |
| Organism | Homo sapiens |
| Length | 81 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- influenza A (H1N1) · score 0.10
- psoriasis · score 0.09
- neurofibrillary tangles measurement · score 0.08
- neoplasm · score 0.08
- serum metabolite measurement · score 0.07
- melanocytic nevus · score 0.06
- dermatitis · score 0.05
- immune deficiency, familial variable · score 0.05
- hyper-IgM syndrome type 3 · score 0.04
- Hodgkins lymphoma · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWK7-F1 | alphafold | PREDICTED | 69.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWK7.
Amino-acid sequence (81 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GPR15LG?
The strongest Open Targets associations for GPR15LG are influenza A (H1N1), psoriasis, neurofibrillary tangles measurement, neoplasm and serum metabolite measurement.
How long is the GPR15LG protein?
The Homo sapiens GPR15LG protein (UniProt Q6UWK7) is 81 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWK7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWK7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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