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Sushi domain-containing protein 1 (SUSD1)

Homo sapiens — UniProt Q6UWL2

Gene: SUSD1Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Sushi domain-containing protein 1 (SUSD1) is a protein from Homo sapiens identified by UniProt accession Q6UWL2, 747 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

  • UniProt accession: Q6UWL2; gene symbol SUSD1.
  • Organism: Homo sapiens.
  • Length: 747 amino acids.
  • Top disease associations (Open Targets): mean corpuscular hemoglobin concentration, hemoglobin measurement and Red cell distribution width.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSushi domain-containing protein 1
UniProt accessionQ6UWL2
GeneSUSD1
OrganismHomo sapiens
Length747 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (73)

Diseases linked to this target (Open Targets).

  • mean corpuscular hemoglobin concentration · score 0.53
  • hemoglobin measurement · score 0.51
  • Red cell distribution width · score 0.50
  • erythrocyte count · score 0.49
  • mean corpuscular hemoglobin · score 0.49
  • mean corpuscular volume · score 0.49
  • testosterone measurement · score 0.44
  • reticulocyte measurement · score 0.44
  • hematocrit · score 0.42
  • reticulocyte count · score 0.39

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6UWL2-F1alphafoldPREDICTED77.81—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWL2.

Amino-acid sequence (747 residues)

MGRGPWDAGP SRRLLPLLLL LGLARGAAGA PGPDGLDVCA TCHEHATCQQ REGKKICICN YGFVGNGRTQ CVDKNECQFG ATLVCGNHTS CHNTPGGFYC ICLEGYRATN NNKTFIPNDG TFCTDIDECE VSGLCRHGGR CVNTHGSFEC YCMDGYLPRN GPEPFHPTTD ATSCTEIDCG TPPEVPDGYI IGNYTSSLGS QVRYACREGF FSVPEDTVSS CTGLGTWESP KLHCQEINCG NPPEMRHAIL VGNHSSRLGG VARYVCQEGF ESPGGKITSV CTEKGTWRES TLTCTEILTK INDVSLFNDT CVRWQINSRR INPKISYVIS IKGQRLDPME SVREETVNLT TDSRTPEVCL ALYPGTNYTV NISTAPPRRS MPAVIGFQTA EVDLLEDDGS FNISIFNETC LKLNRRSRKV GSEHMYQFTV LGQRWYLANF SHATSFNFTT REQVPVVCLD LYPTTDYTVN VTLLRSPKRH SVQITIATPP AVKQTISNIS GFNETCLRWR SIKTADMEEM YLFHIWGQRW YQKEFAQEMT FNISSSSRDP EVCLDLRPGT NYNVSLRALS SELPVVISLT TQITEPPLPE VEFFTVHRGP LPRLRLRKAK EKNGPISSYQ VLVLPLALQS TFSCDSEGAS SFFSNASDAD GYVAAELLAK DVPDDAMEIP IGDRLYYGEY YNAPLKRGSD YCIILRITSE WNKVRRHSCA VWAQVKDSSL MLLQMAGVGL GSLAVVIILT FLSFSAV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SUSD1?

The strongest Open Targets associations for SUSD1 are mean corpuscular hemoglobin concentration, hemoglobin measurement, Red cell distribution width, erythrocyte count and mean corpuscular hemoglobin.

How long is the SUSD1 protein?

The Homo sapiens SUSD1 protein (UniProt Q6UWL2) is 747 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6UWL2
GeneSUSD1
OrganismHomo sapiens
Length747
Binders0
Diseases73
View on UniProt