Dehydrogenase/reductase SDR family member 11 (DHRS11)
Homo sapiens — UniProt Q6UWP2
Data last refreshed: (UniProt release unknown)
Key facts
Dehydrogenase/reductase SDR family member 11 (DHRS11) is a protein from Homo sapiens identified by UniProt accession Q6UWP2, 260 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q6UWP2; gene symbol DHRS11.
- Organism: Homo sapiens.
- Length: 260 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, macrophage inflammatory protein 1b measurement and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dehydrogenase/reductase SDR family member 11 |
|---|---|
| UniProt accession | Q6UWP2 |
| Gene | DHRS11 |
| Organism | Homo sapiens |
| Length | 260 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.43
- macrophage inflammatory protein 1b measurement · score 0.25
- body mass index · score 0.24
- mathematical ability · score 0.18
- blood protein measurement · score 0.18
- cystatin C measurement · score 0.16
- creatinine measurement · score 0.16
- mean reticulocyte volume · score 0.14
- body fat percentage · score 0.10
- lean body mass · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWP2-F1 | alphafold | PREDICTED | 97.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWP2.
Amino-acid sequence (260 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DHRS11?
The strongest Open Targets associations for DHRS11 are neurodegenerative disease, macrophage inflammatory protein 1b measurement, body mass index, mathematical ability and blood protein measurement.
How long is the DHRS11 protein?
The Homo sapiens DHRS11 protein (UniProt Q6UWP2) is 260 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWP2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWP2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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