Lysocardiolipin acyltransferase 1 (LCLAT1)
Homo sapiens — UniProt Q6UWP7
Data last refreshed: (UniProt release unknown)
Key facts
Lysocardiolipin acyltransferase 1 (LCLAT1) is a protein from Homo sapiens identified by UniProt accession Q6UWP7, 414 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.
- UniProt accession: Q6UWP7; gene symbol LCLAT1.
- Organism: Homo sapiens.
- Length: 414 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, eosinophil count and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysocardiolipin acyltransferase 1 |
|---|---|
| UniProt accession | Q6UWP7 |
| Gene | LCLAT1 |
| Organism | Homo sapiens |
| Length | 414 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (96)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.42
- eosinophil count · score 0.39
- neurodegenerative disease · score 0.37
- protein measurement · score 0.31
- hair shape measurement · score 0.31
- balding measurement · score 0.30
- Eczematoid dermatitis · score 0.29
- total blood protein measurement · score 0.28
- heel bone mineral density · score 0.28
- alopecia · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWP7-F1 | alphafold | PREDICTED | 89.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWP7.
Amino-acid sequence (414 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LCLAT1?
The strongest Open Targets associations for LCLAT1 are alkaline phosphatase measurement, eosinophil count, neurodegenerative disease, protein measurement and hair shape measurement.
How long is the LCLAT1 protein?
The Homo sapiens LCLAT1 protein (UniProt Q6UWP7) is 414 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWP7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWP7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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