Suprabasin (SBSN)
Homo sapiens — UniProt Q6UWP8
Data last refreshed: (UniProt release unknown)
Key facts
Suprabasin (SBSN) is a protein from Homo sapiens identified by UniProt accession Q6UWP8, 590 residues long. MolForge cross-references it against 0 known binders and 59 disease associations.
- UniProt accession: Q6UWP8; gene symbol SBSN.
- Organism: Homo sapiens.
- Length: 590 amino acids.
- Top disease associations (Open Targets): esophageal squamous cell carcinoma, myelodysplastic syndrome and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Suprabasin |
|---|---|
| UniProt accession | Q6UWP8 |
| Gene | SBSN |
| Organism | Homo sapiens |
| Length | 590 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (59)
Diseases linked to this target (Open Targets).
- esophageal squamous cell carcinoma · score 0.08
- myelodysplastic syndrome · score 0.08
- platelet count · score 0.06
- Intrahepatic cholestasis of pregnancy · score 0.06
- serum alanine aminotransferase measurement · score 0.05
- platelet crit · score 0.05
- non-small cell lung carcinoma · score 0.05
- cholelithiasis · score 0.05
- cholestasis, intrahepatic, of pregnancy 3 · score 0.04
- neoplasm · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWP8-F1 | alphafold | PREDICTED | 51.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWP8.
Amino-acid sequence (590 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SBSN?
The strongest Open Targets associations for SBSN are esophageal squamous cell carcinoma, myelodysplastic syndrome, platelet count, Intrahepatic cholestasis of pregnancy and serum alanine aminotransferase measurement.
How long is the SBSN protein?
The Homo sapiens SBSN protein (UniProt Q6UWP8) is 590 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWP8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWP8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.