Insulin growth factor-like family member 2 (IGFL2)
Homo sapiens — UniProt Q6UWQ7
Data last refreshed: (UniProt release unknown)
Key facts
Insulin growth factor-like family member 2 (IGFL2) is a protein from Homo sapiens identified by UniProt accession Q6UWQ7, 119 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q6UWQ7; gene symbol IGFL2.
- Organism: Homo sapiens.
- Length: 119 amino acids.
- Top disease associations (Open Targets): lipid measurement, cancer and nonpapillary renal cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Insulin growth factor-like family member 2 |
|---|---|
| UniProt accession | Q6UWQ7 |
| Gene | IGFL2 |
| Organism | Homo sapiens |
| Length | 119 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- lipid measurement · score 0.10
- cancer · score 0.08
- nonpapillary renal cell carcinoma · score 0.08
- renal cell carcinoma · score 0.08
- neoplasm · score 0.07
- non-small cell lung carcinoma · score 0.04
- visceral Leishmaniasis · score 0.03
- psoriasis · score 0.02
- bladder transitional cell carcinoma · score 0.02
- immature platelet fraction · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWQ7-F1 | alphafold | PREDICTED | 73.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWQ7.
Amino-acid sequence (119 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGFL2?
The strongest Open Targets associations for IGFL2 are lipid measurement, cancer, nonpapillary renal cell carcinoma, renal cell carcinoma and neoplasm.
How long is the IGFL2 protein?
The Homo sapiens IGFL2 protein (UniProt Q6UWQ7) is 119 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWQ7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWQ7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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