Glycerophosphocholine cholinephosphodiesterase ENPP6 (ENPP6)
Homo sapiens — UniProt Q6UWR7
Data last refreshed: (UniProt release unknown)
Key facts
Glycerophosphocholine cholinephosphodiesterase ENPP6 (ENPP6) is a protein from Homo sapiens identified by UniProt accession Q6UWR7, 440 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.
- UniProt accession: Q6UWR7; gene symbol ENPP6.
- Organism: Homo sapiens.
- Length: 440 amino acids.
- Top disease associations (Open Targets): protein measurement, influenza A (H1N1) and diastolic blood pressure.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycerophosphocholine cholinephosphodiesterase ENPP6 |
|---|---|
| UniProt accession | Q6UWR7 |
| Gene | ENPP6 |
| Organism | Homo sapiens |
| Length | 440 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (48)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.33
- influenza A (H1N1) · score 0.33
- diastolic blood pressure · score 0.33
- psychotic symptoms · score 0.33
- heel bone mineral density · score 0.31
- glioblastoma multiforme · score 0.23
- breast adenocarcinoma · score 0.23
- chronic lymphocytic leukemia · score 0.22
- PHF-tau measurement · score 0.21
- hippocampal tail volume · score 0.19
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWR7-F1 | alphafold | PREDICTED | 92.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWR7.
Amino-acid sequence (440 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ENPP6?
The strongest Open Targets associations for ENPP6 are protein measurement, influenza A (H1N1), diastolic blood pressure, psychotic symptoms and heel bone mineral density.
How long is the ENPP6 protein?
The Homo sapiens ENPP6 protein (UniProt Q6UWR7) is 440 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWR7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWR7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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