Protein PET117 homolog, mitochondrial (PET117)
Homo sapiens — UniProt Q6UWS5
Data last refreshed: (UniProt release unknown)
Key facts
Protein PET117 homolog, mitochondrial (PET117) is a protein from Homo sapiens identified by UniProt accession Q6UWS5, 81 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q6UWS5; gene symbol PET117.
- Organism: Homo sapiens.
- Length: 81 amino acids.
- Top disease associations (Open Targets): mitochondrial complex 4 deficiency, nuclear type 19, Isolated cytochrome C oxidase deficiency and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein PET117 homolog, mitochondrial |
|---|---|
| UniProt accession | Q6UWS5 |
| Gene | PET117 |
| Organism | Homo sapiens |
| Length | 81 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- mitochondrial complex 4 deficiency, nuclear type 19 · score 0.46
- Isolated cytochrome C oxidase deficiency · score 0.37
- neurodegenerative disease · score 0.30
- triple-negative breast cancer · score 0.01
- ulcerative colitis · score 0.01
- Leigh syndrome · score 0.00
- hepatocellular carcinoma · score 0.00
- mitochondrial disease · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWS5-F1 | alphafold | PREDICTED | 94.94 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWS5.
Amino-acid sequence (81 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PET117?
The strongest Open Targets associations for PET117 are mitochondrial complex 4 deficiency, nuclear type 19, Isolated cytochrome C oxidase deficiency, neurodegenerative disease, triple-negative breast cancer and ulcerative colitis.
How long is the PET117 protein?
The Homo sapiens PET117 protein (UniProt Q6UWS5) is 81 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWS5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWS5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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