Protein PET117 homolog, mitochondrial (PET117)

About Protein PET117 homolog, mitochondrial

Protein PET117 homolog, mitochondrial (PET117) is a protein from Homo sapiens identified by UniProt accession Q6UWS5, 81 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.

Target properties

Protein name	Protein PET117 homolog, mitochondrial
UniProt accession	Q6UWS5
Gene	PET117
Organism	Homo sapiens
Length	81 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (9)

Diseases linked to this target (Open Targets).

mitochondrial complex 4 deficiency, nuclear type 19 · score 0.46
Isolated cytochrome C oxidase deficiency · score 0.37
neurodegenerative disease · score 0.30
triple-negative breast cancer · score 0.01
ulcerative colitis · score 0.01
Leigh syndrome · score 0.00
hepatocellular carcinoma · score 0.00
mitochondrial disease · score 0.00
neoplasm · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UWS5-F1	alphafold	PREDICTED	94.94	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWS5.

Amino-acid sequence (81 residues)

MSRSSKVVLG LSVLLTAATV AGVHVKQQWD QQRLRDGVIR DIERQIRKKE NIRLLGEQII LTEQLEAERE KMLLAKGSQK S

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards