Adropin (ENHO)
Homo sapiens — UniProt Q6UWT2
Data last refreshed: (UniProt release unknown)
Key facts
Adropin (ENHO) is a protein from Homo sapiens identified by UniProt accession Q6UWT2, 76 residues long. MolForge cross-references it against 0 known binders and 216 disease associations.
- UniProt accession: Q6UWT2; gene symbol ENHO.
- Organism: Homo sapiens.
- Length: 76 amino acids.
- Top disease associations (Open Targets): neoplasm, non-alcoholic steatohepatitis and inherited lipid metabolism disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Adropin |
|---|---|
| UniProt accession | Q6UWT2 |
| Gene | ENHO |
| Organism | Homo sapiens |
| Length | 76 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (216)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.08
- non-alcoholic steatohepatitis · score 0.08
- inherited lipid metabolism disorder · score 0.06
- chronic kidney disease · score 0.06
- stroke · score 0.06
- Stroke · score 0.06
- PLIN1-related familial partial lipodystrophy · score 0.06
- CIDEC-related familial partial lipodystrophy · score 0.05
- PPARG-related familial partial lipodystrophy · score 0.05
- obesity due to melanocortin 4 receptor deficiency · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWT2-F1 | alphafold | PREDICTED | 74.34 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWT2.
Amino-acid sequence (76 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ENHO?
The strongest Open Targets associations for ENHO are neoplasm, non-alcoholic steatohepatitis, inherited lipid metabolism disorder, chronic kidney disease and stroke.
How long is the ENHO protein?
The Homo sapiens ENHO protein (UniProt Q6UWT2) is 76 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWT2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWT2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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