Uncharacterized protein C5orf46 (C5orf46)
Homo sapiens — UniProt Q6UWT4
Data last refreshed: (UniProt release unknown)
Key facts
Uncharacterized protein C5orf46 (C5orf46) is a protein from Homo sapiens identified by UniProt accession Q6UWT4, 87 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.
- UniProt accession: Q6UWT4; gene symbol C5orf46.
- Organism: Homo sapiens.
- Length: 87 amino acids.
- Top disease associations (Open Targets): neoplasm, cancer and cholesterol-ester transfer protein deficiency.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Uncharacterized protein C5orf46 |
|---|---|
| UniProt accession | Q6UWT4 |
| Gene | C5orf46 |
| Organism | Homo sapiens |
| Length | 87 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (37)
Diseases linked to this target (Open Targets).
- neoplasm · score 0.07
- cancer · score 0.05
- cholesterol-ester transfer protein deficiency · score 0.04
- colorectal cancer · score 0.04
- hypertriglyceridemia 2 · score 0.04
- Combined hyperlipidemia · score 0.03
- psoriasis · score 0.03
- Meningitis · score 0.03
- clear cell renal carcinoma · score 0.03
- atopic eczema · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWT4-F1 | alphafold | PREDICTED | 65.01 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWT4.
Amino-acid sequence (87 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C5orf46?
The strongest Open Targets associations for C5orf46 are neoplasm, cancer, cholesterol-ester transfer protein deficiency, colorectal cancer and hypertriglyceridemia 2.
How long is the C5orf46 protein?
The Homo sapiens C5orf46 protein (UniProt Q6UWT4) is 87 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWT4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWT4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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