Beta-galactosidase-1-like protein (GLB1L)
Homo sapiens — UniProt Q6UWU2
Data last refreshed: (UniProt release unknown)
Key facts
Beta-galactosidase-1-like protein (GLB1L) is a protein from Homo sapiens identified by UniProt accession Q6UWU2, 654 residues long. MolForge cross-references it against 0 known binders and 19 disease associations.
- UniProt accession: Q6UWU2; gene symbol GLB1L.
- Organism: Homo sapiens.
- Length: 654 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, platelet component distribution width and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-galactosidase-1-like protein |
|---|---|
| UniProt accession | Q6UWU2 |
| Gene | GLB1L |
| Organism | Homo sapiens |
| Length | 654 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (19)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.18
- platelet component distribution width · score 0.13
- reticulocyte count · score 0.12
- cutaneous melanoma · score 0.10
- mean platelet volume · score 0.09
- reticulocyte measurement · score 0.07
- lymphocyte count · score 0.05
- Red cell distribution width · score 0.04
- low density lipoprotein cholesterol measurement · score 0.03
- sex hormone-binding globulin measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWU2-F1 | alphafold | PREDICTED | 90.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWU2.
Amino-acid sequence (654 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GLB1L?
The strongest Open Targets associations for GLB1L are triglyceride measurement, platelet component distribution width, reticulocyte count, cutaneous melanoma and mean platelet volume.
How long is the GLB1L protein?
The Homo sapiens GLB1L protein (UniProt Q6UWU2) is 654 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWU2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWU2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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