Bombesin receptor-activated protein C6orf89 (C6orf89)
Homo sapiens — UniProt Q6UWU4
Data last refreshed: (UniProt release unknown)
Key facts
Bombesin receptor-activated protein C6orf89 (C6orf89) is a protein from Homo sapiens identified by UniProt accession Q6UWU4, 347 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q6UWU4; gene symbol C6orf89.
- Organism: Homo sapiens.
- Length: 347 amino acids.
- Top disease associations (Open Targets): blood protein measurement, genetic disorder and heart rate variability measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Bombesin receptor-activated protein C6orf89 |
|---|---|
| UniProt accession | Q6UWU4 |
| Gene | C6orf89 |
| Organism | Homo sapiens |
| Length | 347 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.20
- genetic disorder · score 0.12
- heart rate variability measurement · score 0.09
- heart rate response to exercise · score 0.06
- resting heart rate · score 0.06
- metabolite measurement · score 0.05
- unipolar depression · score 0.05
- pulse pressure measurement · score 0.04
- diet measurement · score 0.03
- acute kidney failure · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWU4-F1 | alphafold | PREDICTED | 72.46 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWU4.
Amino-acid sequence (347 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with C6orf89?
The strongest Open Targets associations for C6orf89 are blood protein measurement, genetic disorder, heart rate variability measurement, heart rate response to exercise and resting heart rate.
How long is the C6orf89 protein?
The Homo sapiens C6orf89 protein (UniProt Q6UWU4) is 347 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWU4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWU4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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