Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7)
Homo sapiens — UniProt Q6UWV6
Data last refreshed: (UniProt release unknown)
Key facts
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7) is a protein from Homo sapiens identified by UniProt accession Q6UWV6, 458 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.
- UniProt accession: Q6UWV6; gene symbol ENPP7.
- Organism: Homo sapiens.
- Length: 458 amino acids.
- Top disease associations (Open Targets): blood protein measurement, prostate carcinoma and Familial prostate cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 |
|---|---|
| UniProt accession | Q6UWV6 |
| Gene | ENPP7 |
| Organism | Homo sapiens |
| Length | 458 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (71)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.35
- prostate carcinoma · score 0.11
- Familial prostate cancer · score 0.11
- prostate cancer · score 0.11
- colitis · score 0.06
- Diarrhea, Infantile · score 0.05
- annular pancreas · score 0.05
- Congenital malabsorptive diarrhea due to paucity of enteroendocrine cells · score 0.05
- Meckel's diverticulum · score 0.04
- bile acid malabsorption, primary, 1 · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWV6-F1 | alphafold | PREDICTED | 90.13 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWV6.
Amino-acid sequence (458 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ENPP7?
The strongest Open Targets associations for ENPP7 are blood protein measurement, prostate carcinoma, Familial prostate cancer, prostate cancer and colitis.
How long is the ENPP7 protein?
The Homo sapiens ENPP7 protein (UniProt Q6UWV6) is 458 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWV6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWV6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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