Carboxylesterase 3 (CES3)
Homo sapiens — UniProt Q6UWW8
Data last refreshed: (UniProt release unknown)
Key facts
Carboxylesterase 3 (CES3) is a protein from Homo sapiens identified by UniProt accession Q6UWW8, 571 residues long. MolForge cross-references it against 0 known binders and 43 disease associations.
- UniProt accession: Q6UWW8; gene symbol CES3.
- Organism: Homo sapiens.
- Length: 571 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, bone quantitative ultrasound measurement and neurodegenerative disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Carboxylesterase 3 |
|---|---|
| UniProt accession | Q6UWW8 |
| Gene | CES3 |
| Organism | Homo sapiens |
| Length | 571 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (43)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.33
- bone quantitative ultrasound measurement · score 0.27
- neurodegenerative disease · score 0.22
- cutaneous melanoma · score 0.18
- glioblastoma multiforme · score 0.17
- lung adenocarcinoma · score 0.12
- neoplasm · score 0.08
- balding measurement · score 0.07
- erythrocyte count · score 0.05
- myeloid white cell count · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWW8-F1 | alphafold | PREDICTED | 91.57 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWW8.
Amino-acid sequence (571 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CES3?
The strongest Open Targets associations for CES3 are heel bone mineral density, bone quantitative ultrasound measurement, neurodegenerative disease, cutaneous melanoma and glioblastoma multiforme.
How long is the CES3 protein?
The Homo sapiens CES3 protein (UniProt Q6UWW8) is 571 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWW8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWW8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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