HHIP-like protein 2 (HHIPL2)
Homo sapiens — UniProt Q6UWX4
Data last refreshed: (UniProt release unknown)
Key facts
HHIP-like protein 2 (HHIPL2) is a protein from Homo sapiens identified by UniProt accession Q6UWX4, 724 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q6UWX4; gene symbol HHIPL2.
- Organism: Homo sapiens.
- Length: 724 amino acids.
- Top disease associations (Open Targets): angina pectoris, metabolite measurement and Keloid.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | HHIP-like protein 2 |
|---|---|
| UniProt accession | Q6UWX4 |
| Gene | HHIPL2 |
| Organism | Homo sapiens |
| Length | 724 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- angina pectoris · score 0.16
- metabolite measurement · score 0.15
- Keloid · score 0.13
- reactive cutaneous fibrous lesion · score 0.11
- hypertrophy · score 0.04
- non-small cell lung carcinoma · score 0.04
- hepatocellular carcinoma · score 0.02
- gastric cancer · score 0.02
- cancer · score 0.01
- Down syndrome · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UWX4-F1 | alphafold | PREDICTED | 84.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UWX4.
Amino-acid sequence (724 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HHIPL2?
The strongest Open Targets associations for HHIPL2 are angina pectoris, metabolite measurement, Keloid, reactive cutaneous fibrous lesion and hypertrophy.
How long is the HHIPL2 protein?
The Homo sapiens HHIPL2 protein (UniProt Q6UWX4) is 724 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UWX4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UWX4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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