Protein FAM131A (FAM131A)

About Protein FAM131A

Protein FAM131A (FAM131A) is a protein from Homo sapiens identified by UniProt accession Q6UXB0, 366 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.

Target properties

Protein name	Protein FAM131A
UniProt accession	Q6UXB0
Gene	FAM131A
Organism	Homo sapiens
Length	366 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (31)

Diseases linked to this target (Open Targets).

familial hyperaldosteronism type II · score 0.38
neurodegenerative disease · score 0.32
appendicular lean mass · score 0.21
genetic disorder · score 0.18
leukoencephalopathy with mild cerebellar ataxia and white matter edema · score 0.15
body mass index · score 0.10
intelligence · score 0.06
insomnia · score 0.06
total blood protein measurement · score 0.06
self reported educational attainment · score 0.06

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXB0-F1	alphafold	PREDICTED	52.31	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UXB0.

Amino-acid sequence (366 residues)

MPMISVLGKM FLWQREGPGG RWTCQTSRRV SSDPAWAVEW IELPRGLSLS SLGSARTLRG WSRSSRPSSV DSQDLPEVNV GDTVAMLPKS RRALTIQEIA ALARSSLHGI SQVVKDHVTK PTAMAQGRVA HLIEWKGWSK PSDSPAALES AFSSYSDLSE GEQEARFAAG VAEQFAIAEA KLRAWSSVDG EDSTDDSYDE DFAGGMDTDM AGQLPLGPHL QDLFTGHRFS RPVRQGSVEP ESDCSQTVSP DTLCSSLCSL EDGLLGSPAR LASQLLGDEL LLAKLPPSRE SAFRSLGPLE AQDSLYNSPL TESCLSPAEE EPAPCKDCQP LCPPLTGSWE RQRQASDLAS SGVVSLDEDE AEPEEQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards