Insulin growth factor-like family member 3 (IGFL3)
Homo sapiens — UniProt Q6UXB1
Data last refreshed: (UniProt release unknown)
Key facts
Insulin growth factor-like family member 3 (IGFL3) is a protein from Homo sapiens identified by UniProt accession Q6UXB1, 125 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q6UXB1; gene symbol IGFL3.
- Organism: Homo sapiens.
- Length: 125 amino acids.
- Top disease associations (Open Targets): lipid measurement, psoriasis and non-small cell lung carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Insulin growth factor-like family member 3 |
|---|---|
| UniProt accession | Q6UXB1 |
| Gene | IGFL3 |
| Organism | Homo sapiens |
| Length | 125 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- lipid measurement · score 0.04
- psoriasis · score 0.01
- non-small cell lung carcinoma · score 0.01
- Miyoshi myopathy · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UXB1-F1 | alphafold | PREDICTED | 76.02 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UXB1.
Amino-acid sequence (125 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with IGFL3?
The strongest Open Targets associations for IGFL3 are lipid measurement, psoriasis, non-small cell lung carcinoma, Miyoshi myopathy and neoplasm.
How long is the IGFL3 protein?
The Homo sapiens IGFL3 protein (UniProt Q6UXB1) is 125 amino acids long.
Browse: Targets: I · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UXB1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UXB1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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