C-type lectin domain family 4 member G (CLEC4G)
Homo sapiens — UniProt Q6UXB4
Data last refreshed: (UniProt release unknown)
Key facts
C-type lectin domain family 4 member G (CLEC4G) is a protein from Homo sapiens identified by UniProt accession Q6UXB4, 293 residues long. MolForge cross-references it against 0 known binders and 159 disease associations.
- UniProt accession: Q6UXB4; gene symbol CLEC4G.
- Organism: Homo sapiens.
- Length: 293 amino acids.
- Top disease associations (Open Targets): CD209 antigen measurement, blood protein measurement and infect.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | C-type lectin domain family 4 member G |
|---|---|
| UniProt accession | Q6UXB4 |
| Gene | CLEC4G |
| Organism | Homo sapiens |
| Length | 293 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (159)
Diseases linked to this target (Open Targets).
- CD209 antigen measurement · score 0.22
- blood protein measurement · score 0.13
- infect · score 0.08
- infection · score 0.08
- neutrophil count · score 0.08
- gonorrhea · score 0.07
- hepatocellular carcinoma · score 0.07
- primary familial polycythemia due to EPO receptor mutation · score 0.06
- neutrophil percentage of leukocytes · score 0.06
- Pyruvate kinase hyperactivity · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UXB4-F1 | alphafold | PREDICTED | 89.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UXB4.
Amino-acid sequence (293 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CLEC4G?
The strongest Open Targets associations for CLEC4G are CD209 antigen measurement, blood protein measurement, infect, infection and neutrophil count.
How long is the CLEC4G protein?
The Homo sapiens CLEC4G protein (UniProt Q6UXB4) is 293 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UXB4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UXB4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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