C-type lectin domain family 9 member A (CLEC9A)

About C-type lectin domain family 9 member A

C-type lectin domain family 9 member A (CLEC9A) is a protein from Homo sapiens identified by UniProt accession Q6UXN8, 241 residues long. MolForge cross-references it against 0 known binders and 68 disease associations.

Target properties

Protein name	C-type lectin domain family 9 member A
UniProt accession	Q6UXN8
Gene	CLEC9A
Organism	Homo sapiens
Length	241 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (68)

Diseases linked to this target (Open Targets).

neoplasm · score 0.10
blood protein measurement · score 0.08
lung adenocarcinoma · score 0.07
cancer · score 0.04
chronic obstructive pulmonary disease · score 0.03
colitis · score 0.02
eosinophil count · score 0.02
psoriatic arthritis · score 0.02
infection · score 0.02
infect · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXN8-F1	alphafold	PREDICTED	84.15	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UXN8.

Amino-acid sequence (241 residues)

MHEEEIYTSL QWDSPAPDTY QKCLSSNKCS GACCLVMVIS CVFCMGLLTA SIFLGVKLLQ VSTIAMQQQE KLIQQERALL NFTEWKRSCA LQMKYCQAFM QNSLSSAHNS SPCPNNWIQN RESCYYVSEI WSIWHTSQEN CLKEGSTLLQ IESKEEMDFI TGSLRKIKGS YDYWVGLSQD GHSGRWLWQD GSSPSPGLLP AERSQSANQV CGYVKSNSLL SSNCSTWKYF ICEKYALRSS V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards