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Protein FAM151B (FAM151B)

Homo sapiens — UniProt Q6UXP7

Gene: FAM151BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein FAM151B (FAM151B) is a protein from Homo sapiens identified by UniProt accession Q6UXP7, 276 residues long. MolForge cross-references it against 0 known binders and 80 disease associations.

  • UniProt accession: Q6UXP7; gene symbol FAM151B.
  • Organism: Homo sapiens.
  • Length: 276 amino acids.
  • Top disease associations (Open Targets): hair color, psoriasis and hair colour measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein FAM151B
UniProt accessionQ6UXP7
GeneFAM151B
OrganismHomo sapiens
Length276 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (80)

Diseases linked to this target (Open Targets).

  • hair color · score 0.12
  • psoriasis · score 0.11
  • hair colour measurement · score 0.11
  • retinitis pigmentosa · score 0.08
  • X-linked retinal dysplasia · score 0.07
  • age-related macular degeneration · score 0.07
  • Familial exudative vitreoretinopathy · score 0.06
  • choroidal dystrophy, central areolar, 1 · score 0.06
  • Familial drusen · score 0.06
  • Cone rod dystrophy · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6UXP7-F1alphafoldPREDICTED94.61—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UXP7.

Amino-acid sequence (276 residues)

MAASAGGPGS WSENILEYFL RNSQITAEDG AEITWYHAAN HKAQTNEALK STAHMIEADV LLPSDGSEHS QPIMAHPPET NSDNTLQEWL TEVMKSNKGI KLDFKSLAVV EPSMMLLENV KRHLKRPVWI NADILPGPNG NSKVIDAKPF LDTVISFFPD VTFSLGWTTG WHPEKVNEGY SWTMVKEMEY ICNELSQPVT FPVRAALVRQ SCSQLLWLLK KSNRYSLTIW TGKNDNYSVE DLLYIRDHFD KKQVFYDILE PQNHEFKQAI GIKVNL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with FAM151B?

The strongest Open Targets associations for FAM151B are hair color, psoriasis, hair colour measurement, retinitis pigmentosa and X-linked retinal dysplasia.

How long is the FAM151B protein?

The Homo sapiens FAM151B protein (UniProt Q6UXP7) is 276 amino acids long.

Browse: Targets: F · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6UXP7
GeneFAM151B
OrganismHomo sapiens
Length276
Binders0
Diseases80
View on UniProt