Protein ABHD15 (ABHD15)

About Protein ABHD15

Protein ABHD15 (ABHD15) is a protein from Homo sapiens identified by UniProt accession Q6UXT9, 468 residues long. MolForge cross-references it against 0 known binders and 33 disease associations.

Target properties

Protein name	Protein ABHD15
UniProt accession	Q6UXT9
Gene	ABHD15
Organism	Homo sapiens
Length	468 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (33)

Diseases linked to this target (Open Targets).

body height · score 0.49
BMI-adjusted hip circumference · score 0.35
mean platelet volume · score 0.33
neurodegenerative disease · score 0.30
high density lipoprotein cholesterol measurement · score 0.29
triglyceride measurement · score 0.29
sitting height measurement · score 0.28
forced expiratory volume · score 0.27
hip circumference · score 0.24
fat body mass · score 0.13

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6UXT9-F1	alphafold	PREDICTED	79.40	—

Amino-acid sequence (468 residues)

MPPWGAALAL ILAVLALLGL LGPRLRGPWG RAVGERTLPG AQDRDDGEEA DGGGPADQFS DGREPLPGGC SLVCKPSALA QCLLRALRRS EALEAGPRSW FSGPHLQTLC HFVLPVAPGP ELAREYLQLA DDGLVALDWV VGPCVRGRRI TSAGGLPAVL LVIPNAWGRL TRNVLGLCLL ALERGYYPVI FHRRGHHGCP LVSPRLQPFG DPSDLKEAVT YIRFRHPAAP LFAVSEGSGS ALLLSYLGEC GSSSYVTGAA CISPVLRCRE WFEAGLPWPY ERGFLLHQKI ALSRYATALE DTVDTSRLFR SRSLREFEEA LFCHTKSFPI SWDTYWDRND PLRDVDEAAV PVLCICSADD PVCGPPDHTL TTELFHSNPY FFLLLSRHGG HCGFLRQEPL PAWSHEVILE SFRALTEFFR TEERIKGLSR HRASFLGGRR RGGALQRREV SSSSNLEEIF NWKRSYTR

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards