Netrin receptor UNC5D (UNC5D)
Homo sapiens — UniProt Q6UXZ4
Data last refreshed: (UniProt release unknown)
Key facts
Netrin receptor UNC5D (UNC5D) is a protein from Homo sapiens identified by UniProt accession Q6UXZ4, 953 residues long. MolForge cross-references it against 0 known binders and 84 disease associations.
- UniProt accession: Q6UXZ4; gene symbol UNC5D.
- Organism: Homo sapiens.
- Length: 953 amino acids.
- Top disease associations (Open Targets): insomnia measurement, chronotype measurement and wellbeing measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Netrin receptor UNC5D |
|---|---|
| UniProt accession | Q6UXZ4 |
| Gene | UNC5D |
| Organism | Homo sapiens |
| Length | 953 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (84)
Diseases linked to this target (Open Targets).
- insomnia measurement · score 0.37
- chronotype measurement · score 0.37
- wellbeing measurement · score 0.35
- brain measurement · score 0.30
- diet measurement · score 0.30
- blood protein measurement · score 0.29
- protein measurement · score 0.29
- adolescent idiopathic scoliosis · score 0.29
- mathematical ability · score 0.29
- intestinal obstruction · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UXZ4-F1 | alphafold | PREDICTED | 74.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UXZ4.
Amino-acid sequence (953 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UNC5D?
The strongest Open Targets associations for UNC5D are insomnia measurement, chronotype measurement, wellbeing measurement, brain measurement and diet measurement.
How long is the UNC5D protein?
The Homo sapiens UNC5D protein (UniProt Q6UXZ4) is 953 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UXZ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UXZ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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