Leucine-rich repeat-containing protein 31 (LRRC31)
Homo sapiens — UniProt Q6UY01
Data last refreshed: (UniProt release unknown)
Key facts
Leucine-rich repeat-containing protein 31 (LRRC31) is a protein from Homo sapiens identified by UniProt accession Q6UY01, 552 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q6UY01; gene symbol LRRC31.
- Organism: Homo sapiens.
- Length: 552 amino acids.
- Top disease associations (Open Targets): central nervous system cancer, monocyte percentage of leukocytes and sclerosing cholangitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leucine-rich repeat-containing protein 31 |
|---|---|
| UniProt accession | Q6UY01 |
| Gene | LRRC31 |
| Organism | Homo sapiens |
| Length | 552 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- central nervous system cancer · score 0.23
- monocyte percentage of leukocytes · score 0.17
- sclerosing cholangitis · score 0.15
- renal cell carcinoma · score 0.11
- platelet crit · score 0.10
- multiple sclerosis · score 0.08
- Barrett's esophagus · score 0.07
- erythrocyte count · score 0.05
- sitting height measurement · score 0.05
- neoplasm · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UY01-F1 | alphafold | PREDICTED | 85.62 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UY01.
Amino-acid sequence (552 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LRRC31?
The strongest Open Targets associations for LRRC31 are central nervous system cancer, monocyte percentage of leukocytes, sclerosing cholangitis, renal cell carcinoma and platelet crit.
How long is the LRRC31 protein?
The Homo sapiens LRRC31 protein (UniProt Q6UY01) is 552 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UY01 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UY01 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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