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Cell adhesion molecule CEACAM20 (CEACAM20)

Homo sapiens — UniProt Q6UY09

Gene: CEACAM20Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cell adhesion molecule CEACAM20 (CEACAM20) is a protein from Homo sapiens identified by UniProt accession Q6UY09, 596 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.

  • UniProt accession: Q6UY09; gene symbol CEACAM20.
  • Organism: Homo sapiens.
  • Length: 596 amino acids.
  • Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, Crohn's disease and pancreatic adenocarcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCell adhesion molecule CEACAM20
UniProt accessionQ6UY09
GeneCEACAM20
OrganismHomo sapiens
Length596 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (10)

Diseases linked to this target (Open Targets).

  • low density lipoprotein cholesterol measurement · score 0.17
  • Crohn's disease · score 0.05
  • pancreatic adenocarcinoma · score 0.04
  • Colon Sessile Serrated Adenoma/Polyp · score 0.01
  • diffuse large B-cell lymphoma · score 0.00
  • intrahepatic cholangiocarcinoma · score 0.00
  • prostate carcinoma · score 0.00
  • neoplasm · score 0.00
  • colitis · score 0.00
  • inflammatory bowel disease · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6UY09-F1alphafoldPREDICTED73.98—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UY09.

Amino-acid sequence (596 residues)

MGPADSWGHH WMGILLSASL CTVWSPPAAA QLTLNANPLD ATQSEDVVLP VFGTPRTPQI HGRSRELAKP SIAVSPGTAI EQKDMVTFYC TTKDVNITIH WVSNNLSIVF HERMQLSKDG KILTILIVQR EDSGTYQCEA RDALLSQRSD PIFLDVKYGP DPVEIKLESG VASGEVVEVM EGSSMTFLAE TKSHPPCAYT WFLLDSILSH TTRTFTIHAV SREHEGLYRC LVSNSATHLS SLGTLKVRVL ETLTMPQVVP SSLNLVENAR SVDLTCQTVN QSVNVQWFLS GQPLLPSEHL QLSADNRTLI IHGLQRNDTG PYACEVWNWG SRARSEPLEL TINYGPDQVH ITRESASEMI STIEAELNSS LTLQCWAESK PGAEYRWTLE HSTGEHLGEQ LIIRALTWEH DGIYNCTASN SLTGLARSTS VLVKVVGPQS SSLSSGAIAG IVIGILAVIA VASELGYFLC IRNARRPSRK TTEDPSHETS QPIPKEEHPT EPSSESLSPE YRNISQLQGR IRVELMQPPD LPEETYETKL PSASRRGNSF SPWKPPPKPL MPPLRLVSTV PKNMESIYEE LVNPEPNTYI QINPSV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CEACAM20?

The strongest Open Targets associations for CEACAM20 are low density lipoprotein cholesterol measurement, Crohn's disease, pancreatic adenocarcinoma, Colon Sessile Serrated Adenoma/Polyp and diffuse large B-cell lymphoma.

How long is the CEACAM20 protein?

The Homo sapiens CEACAM20 protein (UniProt Q6UY09) is 596 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6UY09
GeneCEACAM20
OrganismHomo sapiens
Length596
Binders0
Diseases10
View on UniProt