Protein delta homolog 2 (DLK2)
Homo sapiens — UniProt Q6UY11
Data last refreshed: (UniProt release unknown)
Key facts
Protein delta homolog 2 (DLK2) is a protein from Homo sapiens identified by UniProt accession Q6UY11, 383 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q6UY11; gene symbol DLK2.
- Organism: Homo sapiens.
- Length: 383 amino acids.
- Top disease associations (Open Targets): toll-like receptor 2 measurement, nonpapillary renal cell carcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein delta homolog 2 |
|---|---|
| UniProt accession | Q6UY11 |
| Gene | DLK2 |
| Organism | Homo sapiens |
| Length | 383 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- toll-like receptor 2 measurement · score 0.15
- nonpapillary renal cell carcinoma · score 0.08
- neoplasm · score 0.07
- mathematical ability · score 0.05
- cancer · score 0.03
- autism spectrum disorder · score 0.03
- schizophrenia · score 0.03
- body height · score 0.03
- age-related hearing impairment · score 0.03
- mean corpuscular volume · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6UY11-F1 | alphafold | PREDICTED | 73.85 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UY11.
Amino-acid sequence (383 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DLK2?
The strongest Open Targets associations for DLK2 are toll-like receptor 2 measurement, nonpapillary renal cell carcinoma, neoplasm, mathematical ability and cancer.
How long is the DLK2 protein?
The Homo sapiens DLK2 protein (UniProt Q6UY11) is 383 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6UY11 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6UY11 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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