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Prostate and testis expressed protein 2 (PATE2)

Homo sapiens — UniProt Q6UY27

Gene: PATE2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Prostate and testis expressed protein 2 (PATE2) is a protein from Homo sapiens identified by UniProt accession Q6UY27, 113 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.

  • UniProt accession: Q6UY27; gene symbol PATE2.
  • Organism: Homo sapiens.
  • Length: 113 amino acids.
  • Top disease associations (Open Targets): mean platelet volume, breast carcinoma and platelet count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProstate and testis expressed protein 2
UniProt accessionQ6UY27
GenePATE2
OrganismHomo sapiens
Length113 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (7)

Diseases linked to this target (Open Targets).

  • mean platelet volume · score 0.14
  • breast carcinoma · score 0.04
  • platelet count · score 0.03
  • dilated cardiomyopathy 1I · score 0.03
  • protein measurement · score 0.02
  • prostate carcinoma · score 0.01
  • axial length measurement · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6UY27-F1alphafoldPREDICTED86.08—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6UY27.

Amino-acid sequence (113 residues)

MLVLFLLGTV FLLCPYWGEL HDPIKATEIM CYECKKYHLG LCYGVMTSCS LKHKQSCAVE NFYILTRKGQ SMYHYSKLSC MTSCEDINFL GFTKRVELIC CDHSNYCNLP EGV

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with PATE2?

The strongest Open Targets associations for PATE2 are mean platelet volume, breast carcinoma, platelet count, dilated cardiomyopathy 1I and protein measurement.

How long is the PATE2 protein?

The Homo sapiens PATE2 protein (UniProt Q6UY27) is 113 amino acids long.

Browse: Targets: P · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6UY27
GenePATE2
OrganismHomo sapiens
Length113
Binders0
Diseases7
View on UniProt