Cytochrome P450 26C1 (CYP26C1)
Homo sapiens — UniProt Q6V0L0
Data last refreshed: (UniProt release unknown)
Key facts
Cytochrome P450 26C1 (CYP26C1) is a protein from Homo sapiens identified by UniProt accession Q6V0L0, 522 residues long. MolForge cross-references it against 0 known binders and 84 disease associations.
- UniProt accession: Q6V0L0; gene symbol CYP26C1.
- Organism: Homo sapiens.
- Length: 522 amino acids.
- Top disease associations (Open Targets): focal facial dermal dysplasia type IV, skin neoplasm and triglyceride measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cytochrome P450 26C1 |
|---|---|
| UniProt accession | Q6V0L0 |
| Gene | CYP26C1 |
| Organism | Homo sapiens |
| Length | 522 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (84)
Diseases linked to this target (Open Targets).
- focal facial dermal dysplasia type IV · score 0.53
- skin neoplasm · score 0.37
- triglyceride measurement · score 0.37
- low density lipoprotein cholesterol measurement · score 0.32
- electrocardiography · score 0.31
- aspartate aminotransferase measurement · score 0.29
- eosinophil count · score 0.27
- apolipoprotein B measurement · score 0.27
- IGF-1 measurement · score 0.27
- creatinine measurement · score 0.26
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6V0L0-F1 | alphafold | PREDICTED | 88.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6V0L0.
Amino-acid sequence (522 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CYP26C1?
The strongest Open Targets associations for CYP26C1 are focal facial dermal dysplasia type IV, skin neoplasm, triglyceride measurement, low density lipoprotein cholesterol measurement and electrocardiography.
How long is the CYP26C1 protein?
The Homo sapiens CYP26C1 protein (UniProt Q6V0L0) is 522 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6V0L0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6V0L0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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