Dipeptidyl peptidase 8 (DPP8)
Homo sapiens — UniProt Q6V1X1
Data last refreshed: (UniProt release unknown)
Key facts
Dipeptidyl peptidase 8 (DPP8) is a protein from Homo sapiens identified by UniProt accession Q6V1X1, 898 residues long. MolForge cross-references it against 6 known binders and 91 disease associations.
- UniProt accession: Q6V1X1; gene symbol DPP8.
- Organism: Homo sapiens.
- Length: 898 amino acids.
- Top disease associations (Open Targets): neutrophil count, mean corpuscular hemoglobin and red blood cell density measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Dipeptidyl peptidase 8 |
|---|---|
| UniProt accession | Q6V1X1 |
| Gene | DPP8 |
| Organism | Homo sapiens |
| Length | 898 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (91)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.20
- mean corpuscular hemoglobin · score 0.18
- red blood cell density measurement · score 0.16
- mean corpuscular volume · score 0.15
- heel bone mineral density · score 0.14
- mean corpuscular hemoglobin concentration · score 0.13
- blood protein measurement · score 0.10
- erythrocyte count · score 0.09
- self reported educational attainment · score 0.09
- cognitive function measurement · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6V1X1-F1 | alphafold | PREDICTED | 90.41 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6V1X1.
Amino-acid sequence (898 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with DPP8?
The strongest Open Targets associations for DPP8 are neutrophil count, mean corpuscular hemoglobin, red blood cell density measurement, mean corpuscular volume and heel bone mineral density.
How long is the DPP8 protein?
The Homo sapiens DPP8 protein (UniProt Q6V1X1) is 898 amino acids long.
Browse: Targets: D · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6V1X1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6V1X1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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