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Ran-binding protein 10 (RANBP10)

Homo sapiens — UniProt Q6VN20

Gene: RANBP10Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Ran-binding protein 10 (RANBP10) is a protein from Homo sapiens identified by UniProt accession Q6VN20, 620 residues long. MolForge cross-references it against 0 known binders and 112 disease associations.

  • UniProt accession: Q6VN20; gene symbol RANBP10.
  • Organism: Homo sapiens.
  • Length: 620 amino acids.
  • Top disease associations (Open Targets): lung adenocarcinoma, thyroid gland adenocarcinoma and glioblastoma multiforme.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRan-binding protein 10
UniProt accessionQ6VN20
GeneRANBP10
OrganismHomo sapiens
Length620 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (112)

Diseases linked to this target (Open Targets).

  • lung adenocarcinoma · score 0.23
  • thyroid gland adenocarcinoma · score 0.22
  • glioblastoma multiforme · score 0.20
  • hematocrit · score 0.19
  • endometrial cancer · score 0.18
  • cutaneous melanoma · score 0.18
  • hemoglobin measurement · score 0.18
  • head and neck squamous cell carcinoma · score 0.17
  • genetic disorder · score 0.12
  • high density lipoprotein cholesterol measurement · score 0.09

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6VN20-F1alphafoldPREDICTED77.10—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6VN20.

Amino-acid sequence (620 residues)

MAAATADPGA GNPQPGDSSG GGAGGGLPSP GEQELSRRLQ RLYPAVNQQE TPLPRSWSPK DKYNYIGLSQ GNLRVHYKGH GKNHKDAASV RATHPIPAAC GIYYFEVKIV SKGRDGYMGI GLSAQGVNMN RLPGWDKHSY GYHGDDGHSF CSSGTGQPYG PTFTTGDVIG CCVNLINGTC FYTKNGHSLG IAFTDLPANL YPTVGLQTPG EIVDANFGQQ PFLFDIEDYM REWRAKVQGT VHCFPISARL GEWQAVLQNM VSSYLVHHGY CATATAFARM TETPIQEEQA SIKNRQKIQK LVLEGRVGEA IETTQRFYPG LLEHNPNLLF MLKCRQFVEM VNGTDSEVRS LSSRSPKSQD SYPGSPSLSP RHGPSSSHMH NTGADSPSCS NGVASTKSKQ NHSKYPAPSS SSSSSSSSSS SSPSSVNYSE SNSTDSTKSQ HHSSTSNQET SDSEMEMEAE HYPNGVLGSM STRIVNGAYK HEDLQTDESS MDDRHPRRQL CGGNQAATER IILFGRELQA LSEQLGREYG KNLAHTEMLQ DAFSLLAYSD PWSCPVGQQL DPIQREPVCA ALNSAILESQ NLPKQPPLML ALGQASECLR LMARAGLGSC SFARVDDYLH

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RANBP10?

The strongest Open Targets associations for RANBP10 are lung adenocarcinoma, thyroid gland adenocarcinoma, glioblastoma multiforme, hematocrit and endometrial cancer.

How long is the RANBP10 protein?

The Homo sapiens RANBP10 protein (UniProt Q6VN20) is 620 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6VN20
GeneRANBP10
OrganismHomo sapiens
Length620
Binders0
Diseases112
View on UniProt