Glycerophosphodiester phosphodiesterase domain-containing protein 4 (GDPD4)
Homo sapiens — UniProt Q6W3E5
Data last refreshed: (UniProt release unknown)
Key facts
Glycerophosphodiester phosphodiesterase domain-containing protein 4 (GDPD4) is a protein from Homo sapiens identified by UniProt accession Q6W3E5, 623 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q6W3E5; gene symbol GDPD4.
- Organism: Homo sapiens.
- Length: 623 amino acids.
- Top disease associations (Open Targets): aspartate aminotransferase measurement, body height and fat body mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glycerophosphodiester phosphodiesterase domain-containing protein 4 |
|---|---|
| UniProt accession | Q6W3E5 |
| Gene | GDPD4 |
| Organism | Homo sapiens |
| Length | 623 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- aspartate aminotransferase measurement · score 0.23
- body height · score 0.18
- fat body mass · score 0.04
- protein measurement · score 0.02
- ulcerative colitis · score 0.02
- hearing loss, autosomal recessive · score 0.01
- Usher syndrome · score 0.01
- deafness · score 0.01
- autosomal dominant nonsyndromic hearing loss · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6W3E5-F1 | alphafold | PREDICTED | 78.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6W3E5.
Amino-acid sequence (623 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GDPD4?
The strongest Open Targets associations for GDPD4 are aspartate aminotransferase measurement, body height, fat body mass, protein measurement and ulcerative colitis.
How long is the GDPD4 protein?
The Homo sapiens GDPD4 protein (UniProt Q6W3E5) is 623 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6W3E5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6W3E5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.