Neuropeptide S receptor (NPSR1)
Homo sapiens — UniProt Q6W5P4
Data last refreshed: (UniProt release unknown)
Key facts
Neuropeptide S receptor (NPSR1) is a protein from Homo sapiens identified by UniProt accession Q6W5P4, 371 residues long. MolForge cross-references it against 0 known binders and 137 disease associations.
- UniProt accession: Q6W5P4; gene symbol NPSR1.
- Organism: Homo sapiens.
- Length: 371 amino acids.
- Top disease associations (Open Targets): metabolite measurement, glioblastoma multiforme and PHF-tau measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Neuropeptide S receptor |
|---|---|
| UniProt accession | Q6W5P4 |
| Gene | NPSR1 |
| Organism | Homo sapiens |
| Length | 371 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (137)
Diseases linked to this target (Open Targets).
- metabolite measurement · score 0.29
- glioblastoma multiforme · score 0.26
- PHF-tau measurement · score 0.26
- breast adenocarcinoma · score 0.25
- asthma · score 0.18
- pancreatic adenocarcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.17
- low grade glioma · score 0.14
- anxiety · score 0.09
- exercise · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6W5P4-F1 | alphafold | PREDICTED | 81.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6W5P4.
Amino-acid sequence (371 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NPSR1?
The strongest Open Targets associations for NPSR1 are metabolite measurement, glioblastoma multiforme, PHF-tau measurement, breast adenocarcinoma and asthma.
How long is the NPSR1 protein?
The Homo sapiens NPSR1 protein (UniProt Q6W5P4) is 371 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6W5P4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6W5P4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.