Rab11 family-interacting protein 1 (RAB11FIP1)
Homo sapiens — UniProt Q6WKZ4
Data last refreshed: (UniProt release unknown)
Key facts
Rab11 family-interacting protein 1 (RAB11FIP1) is a protein from Homo sapiens identified by UniProt accession Q6WKZ4, 1283 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q6WKZ4; gene symbol RAB11FIP1.
- Organism: Homo sapiens.
- Length: 1283 amino acids.
- Top disease associations (Open Targets): oral squamous cell carcinoma, MODY and hyperproinsulinemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Rab11 family-interacting protein 1 |
|---|---|
| UniProt accession | Q6WKZ4 |
| Gene | RAB11FIP1 |
| Organism | Homo sapiens |
| Length | 1283 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- oral squamous cell carcinoma · score 0.08
- MODY · score 0.07
- hyperproinsulinemia · score 0.05
- glycogen storage disorder due to hepatic glycogen synthase deficiency · score 0.04
- Glycogen storage disease due to hepatic glycogen synthase deficiency · score 0.04
- breast cancer · score 0.03
- diabetes mellitus, permanent neonatal 4 · score 0.03
- diabetes mellitus, transient neonatal, 3 · score 0.03
- neoplasm · score 0.03
- transient neonatal diabetes mellitus · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6WKZ4-F1 | alphafold | PREDICTED | 46.51 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6WKZ4.
Amino-acid sequence (1283 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RAB11FIP1?
The strongest Open Targets associations for RAB11FIP1 are oral squamous cell carcinoma, MODY, hyperproinsulinemia, glycogen storage disorder due to hepatic glycogen synthase deficiency and Glycogen storage disease due to hepatic glycogen synthase deficiency.
How long is the RAB11FIP1 protein?
The Homo sapiens RAB11FIP1 protein (UniProt Q6WKZ4) is 1283 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6WKZ4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6WKZ4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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