Protein HEPN1 (HEPN1)
Homo sapiens — UniProt Q6WQI6
Data last refreshed: (UniProt release unknown)
Key facts
Protein HEPN1 (HEPN1) is a protein from Homo sapiens identified by UniProt accession Q6WQI6, 88 residues long. MolForge cross-references it against 0 known binders and 8 disease associations.
- UniProt accession: Q6WQI6; gene symbol HEPN1.
- Organism: Homo sapiens.
- Length: 88 amino acids.
- Top disease associations (Open Targets): megalencephalic leukoencephalopathy with subcortical cysts, hepatocellular carcinoma and macula measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein HEPN1 |
|---|---|
| UniProt accession | Q6WQI6 |
| Gene | HEPN1 |
| Organism | Homo sapiens |
| Length | 88 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (8)
Diseases linked to this target (Open Targets).
- megalencephalic leukoencephalopathy with subcortical cysts · score 0.19
- hepatocellular carcinoma · score 0.04
- macula measurement · score 0.02
- breast milk measurement · score 0.02
- protein measurement · score 0.02
- prostate carcinoma · score 0.02
- neoplasm · score 0.01
- Pituitary Gland Adenoma · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6WQI6-F1 | alphafold | PREDICTED | 54.19 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6WQI6.
Amino-acid sequence (88 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with HEPN1?
The strongest Open Targets associations for HEPN1 are megalencephalic leukoencephalopathy with subcortical cysts, hepatocellular carcinoma, macula measurement, breast milk measurement and protein measurement.
How long is the HEPN1 protein?
The Homo sapiens HEPN1 protein (UniProt Q6WQI6) is 88 amino acids long.
Browse: Targets: H · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6WQI6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6WQI6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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