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Secretoglobin family 1D member 4 (SCGB1D4)

Homo sapiens — UniProt Q6XE38

Gene: SCGB1D4Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Secretoglobin family 1D member 4 (SCGB1D4) is a protein from Homo sapiens identified by UniProt accession Q6XE38, 83 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

  • UniProt accession: Q6XE38; gene symbol SCGB1D4.
  • Organism: Homo sapiens.
  • Length: 83 amino acids.
  • Top disease associations (Open Targets): cystatin C measurement, chronic rhinosinusitis with nasal polyps and cancer.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameSecretoglobin family 1D member 4
UniProt accessionQ6XE38
GeneSCGB1D4
OrganismHomo sapiens
Length83 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (23)

Diseases linked to this target (Open Targets).

  • cystatin C measurement · score 0.05
  • chronic rhinosinusitis with nasal polyps · score 0.01
  • cancer · score 0.01
  • mitochondrial DNA depletion syndrome 4a · score 0.01
  • triple-negative breast cancer · score 0.01
  • chronic rhinosinusitis without nasal polyps · score 0.01
  • infection · score 0.01
  • infect · score 0.01
  • Obesity · score 0.00
  • type 2 diabetes mellitus · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6XE38-F1alphafoldPREDICTED88.21—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6XE38.

Amino-acid sequence (83 residues)

MRLSVCLLMV SLALCCYQAH ALVCPAVASE ITVFLFLSDA AVNLQVAKLN PPPEALAAKL EVKHCTDQIS FKKRLSLKKS WWK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SCGB1D4?

The strongest Open Targets associations for SCGB1D4 are cystatin C measurement, chronic rhinosinusitis with nasal polyps, cancer, mitochondrial DNA depletion syndrome 4a and triple-negative breast cancer.

How long is the SCGB1D4 protein?

The Homo sapiens SCGB1D4 protein (UniProt Q6XE38) is 83 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6XE38
GeneSCGB1D4
OrganismHomo sapiens
Length83
Binders0
Diseases23
View on UniProt