Calcium/manganese antiporter SLC30A10 (SLC30A10)
Homo sapiens — UniProt Q6XR72
Data last refreshed: (UniProt release unknown)
Key facts
Calcium/manganese antiporter SLC30A10 (SLC30A10) is a protein from Homo sapiens identified by UniProt accession Q6XR72, 485 residues long. MolForge cross-references it against 0 known binders and 180 disease associations.
- UniProt accession: Q6XR72; gene symbol SLC30A10.
- Organism: Homo sapiens.
- Length: 485 amino acids.
- Top disease associations (Open Targets): Cirrhosis-dystonia-polycythemia-hypermanganesemia syndrome, cirrhosis - dystonia - polycythemia - hypermanganesemia syndrome and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Calcium/manganese antiporter SLC30A10 |
|---|---|
| UniProt accession | Q6XR72 |
| Gene | SLC30A10 |
| Organism | Homo sapiens |
| Length | 485 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (180)
Diseases linked to this target (Open Targets).
- Cirrhosis-dystonia-polycythemia-hypermanganesemia syndrome · score 0.79
- cirrhosis - dystonia - polycythemia - hypermanganesemia syndrome · score 0.67
- reticulocyte count · score 0.48
- heel bone mineral density · score 0.48
- aspartate aminotransferase measurement · score 0.46
- Red cell distribution width · score 0.46
- bone quantitative ultrasound measurement · score 0.44
- calcium measurement · score 0.43
- reticulocyte measurement · score 0.43
- serum alanine aminotransferase measurement · score 0.42
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6XR72-F1 | alphafold | PREDICTED | 67.48 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6XR72.
Amino-acid sequence (485 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC30A10?
The strongest Open Targets associations for SLC30A10 are Cirrhosis-dystonia-polycythemia-hypermanganesemia syndrome, cirrhosis - dystonia - polycythemia - hypermanganesemia syndrome, reticulocyte count, heel bone mineral density and aspartate aminotransferase measurement.
How long is the SLC30A10 protein?
The Homo sapiens SLC30A10 protein (UniProt Q6XR72) is 485 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6XR72 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6XR72 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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