Synaptotagmin-10 (SYT10)
Homo sapiens — UniProt Q6XYQ8
Data last refreshed: (UniProt release unknown)
Key facts
Synaptotagmin-10 (SYT10) is a protein from Homo sapiens identified by UniProt accession Q6XYQ8, 523 residues long. MolForge cross-references it against 0 known binders and 35 disease associations.
- UniProt accession: Q6XYQ8; gene symbol SYT10.
- Organism: Homo sapiens.
- Length: 523 amino acids.
- Top disease associations (Open Targets): heart rate response to recovery post exercise, electrocardiography and resting heart rate.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Synaptotagmin-10 |
|---|---|
| UniProt accession | Q6XYQ8 |
| Gene | SYT10 |
| Organism | Homo sapiens |
| Length | 523 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (35)
Diseases linked to this target (Open Targets).
- heart rate response to recovery post exercise · score 0.47
- electrocardiography · score 0.46
- resting heart rate · score 0.39
- heart rate · score 0.38
- heart rate variability measurement · score 0.38
- heart rate response to exercise · score 0.38
- high density lipoprotein cholesterol measurement · score 0.34
- diet measurement · score 0.32
- BMI-adjusted waist-hip ratio · score 0.31
- neurodegenerative disease · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6XYQ8-F1 | alphafold | PREDICTED | 73.07 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6XYQ8.
Amino-acid sequence (523 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SYT10?
The strongest Open Targets associations for SYT10 are heart rate response to recovery post exercise, electrocardiography, resting heart rate, heart rate and heart rate variability measurement.
How long is the SYT10 protein?
The Homo sapiens SYT10 protein (UniProt Q6XYQ8) is 523 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6XYQ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6XYQ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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