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Neutral amino acid uniporter 4 (SLC36A4)

Homo sapiens — UniProt Q6YBV0

Gene: SLC36A4Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Neutral amino acid uniporter 4 (SLC36A4) is a protein from Homo sapiens identified by UniProt accession Q6YBV0, 504 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

  • UniProt accession: Q6YBV0; gene symbol SLC36A4.
  • Organism: Homo sapiens.
  • Length: 504 amino acids.
  • Top disease associations (Open Targets): chronotype measurement, response to radiation and daytime rest measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameNeutral amino acid uniporter 4
UniProt accessionQ6YBV0
GeneSLC36A4
OrganismHomo sapiens
Length504 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (18)

Diseases linked to this target (Open Targets).

  • chronotype measurement · score 0.32
  • response to radiation · score 0.18
  • daytime rest measurement · score 0.11
  • type 2 diabetes mellitus · score 0.10
  • HbA1c measurement · score 0.09
  • DNA methylation · score 0.07
  • neoplasm · score 0.05
  • Abnormality of refraction · score 0.03
  • cancer · score 0.00
  • dry age related macular degeneration · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6YBV0-F1alphafoldPREDICTED81.92—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6YBV0.

Amino-acid sequence (504 residues)

MEAAATPAAA GAARREELDM DVMRPLINEQ NFDGTSDEEH EQELLPVQKH YQLDDQEGIS FVQTLMHLLK GNIGTGLLGL PLAIKNAGIV LGPISLVFIG IISVHCMHIL VRCSHFLCLR FKKSTLGYSD TVSFAMEVSP WSCLQKQAAW GRSVVDFFLV ITQLGFCSVY IVFLAENVKQ VHEGFLESKV FISNSTNSSN PCERRSVDLR IYMLCFLPFI ILLVFIRELK NLFVLSFLAN VSMAVSLVII YQYVVRNMPD PHNLPIVAGW KKYPLFFGTA VFAFEGIGVV LPLENQMKES KRFPQALNIG MGIVTTLYVT LATLGYMCFH DEIKGSITLN LPQDVWLYQS VKILYSFGIF VTYSIQFYVP AEIIIPGITS KFHTKWKQIC EFGIRSFLVS ITCAGAILIP RLDIVISFVG AVSSSTLALI LPPLVEILTF SKEHYNIWMV LKNISIAFTG VVGFLLGTYI TVEEIIYPTP KVVAGTPQSP FLNLNSTCLT SGLK

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with SLC36A4?

The strongest Open Targets associations for SLC36A4 are chronotype measurement, response to radiation, daytime rest measurement, type 2 diabetes mellitus and HbA1c measurement.

How long is the SLC36A4 protein?

The Homo sapiens SLC36A4 protein (UniProt Q6YBV0) is 504 amino acids long.

Browse: Targets: S · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6YBV0
GeneSLC36A4
OrganismHomo sapiens
Length504
Binders0
Diseases18
View on UniProt