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Cytochrome c oxidase subunit 6B2 (COX6B2)

Homo sapiens — UniProt Q6YFQ2

Gene: COX6B2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Cytochrome c oxidase subunit 6B2 (COX6B2) is a protein from Homo sapiens identified by UniProt accession Q6YFQ2, 88 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.

  • UniProt accession: Q6YFQ2; gene symbol COX6B2.
  • Organism: Homo sapiens.
  • Length: 88 amino acids.
  • Top disease associations (Open Targets): osteoarthritis, hip, neoplasm and smoking status measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCytochrome c oxidase subunit 6B2
UniProt accessionQ6YFQ2
GeneCOX6B2
OrganismHomo sapiens
Length88 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (18)

Diseases linked to this target (Open Targets).

  • osteoarthritis, hip · score 0.10
  • neoplasm · score 0.08
  • smoking status measurement · score 0.07
  • lung adenocarcinoma · score 0.06
  • cancer · score 0.05
  • non-small cell lung carcinoma · score 0.04
  • drug use measurement · score 0.02
  • ulcerative colitis · score 0.01
  • Crohn's disease · score 0.01
  • inflammatory bowel disease · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6YFQ2-F1alphafoldPREDICTED89.06—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6YFQ2.

Amino-acid sequence (88 residues)

MLDVEAQEPP KGKWSTPPFD PRFPSQNQIR NCYQNFLDYH RCLKTRTRRG KSTQPCEYYF RVYHSLCPIS WVESWNEQIK NGIFAGKI

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with COX6B2?

The strongest Open Targets associations for COX6B2 are osteoarthritis, hip, neoplasm, smoking status measurement, lung adenocarcinoma and cancer.

How long is the COX6B2 protein?

The Homo sapiens COX6B2 protein (UniProt Q6YFQ2) is 88 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6YFQ2
GeneCOX6B2
OrganismHomo sapiens
Length88
Binders0
Diseases18
View on UniProt