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CD109 antigen (CD109)

Homo sapiens — UniProt Q6YHK3

Gene: CD109Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

CD109 antigen (CD109) is a protein from Homo sapiens identified by UniProt accession Q6YHK3, 1445 residues long. MolForge cross-references it against 0 known binders and 283 disease associations.

  • UniProt accession: Q6YHK3; gene symbol CD109.
  • Organism: Homo sapiens.
  • Length: 1445 amino acids.
  • Top disease associations (Open Targets): heel bone mineral density, calcium measurement and CD109 antigen measurement.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameCD109 antigen
UniProt accessionQ6YHK3
GeneCD109
OrganismHomo sapiens
Length1445 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (283)

Diseases linked to this target (Open Targets).

  • heel bone mineral density · score 0.52
  • calcium measurement · score 0.48
  • CD109 antigen measurement · score 0.47
  • bone quantitative ultrasound measurement · score 0.47
  • bone density · score 0.41
  • uterine fibroid · score 0.41
  • myocardial infarction · score 0.40
  • blood phosphate measurement · score 0.34
  • blood cadmium measurement · score 0.33
  • blood protein measurement · score 0.33

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6YHK3-F1alphafoldPREDICTED81.26—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6YHK3.

Amino-acid sequence (1445 residues)

MQGPPLLTAA HLLCVCTAAL AVAPGPRFLV TAPGIIRPGG NVTIGVELLE HCPSQVTVKA ELLKTASNLT VSVLEAEGVF EKGSFKTLTL PSLPLNSADE IYELRVTGRT QDEILFSNST RLSFETKRIS VFIQTDKALY KPKQEVKFRI VTLFSDFKPY KTSLNILIKD PKSNLIQQWL SQQSDLGVIS KTFQLSSHPI LGDWSIQVQV NDQTYYQSFQ VSEYVLPKFE VTLQTPLYCS MNSKHLNGTI TAKYTYGKPV KGDVTLTFLP LSFWGKKKNI TKTFKINGSA NFSFNDEEMK NVMDSSNGLS EYLDLSSPGP VEILTTVTES VTGISRNVST NVFFKQHDYI IEFFDYTTVL KPSLNFTATV KVTRADGNQL TLEERRNNVV ITVTQRNYTE YWSGSNSGNQ KMEAVQKINY TVPQSGTFKI EFPILEDSSE LQLKAYFLGS KSSMAVHSLF KSPSKTYIQL KTRDENIKVG SPFELVVSGN KRLKELSYMV VSRGQLVAVG KQNSTMFSLT PENSWTPKAC VIVYYIEDDG EIISDVLKIP VQLVFKNKIK LYWSKVKAEP SEKVSLRISV TQPDSIVGIV AVDKSVNLMN ASNDITMENV VHELELYNTG YYLGMFMNSF AVFQECGLWV LTDANLTKDY IDGVYDNAEY AERFMEENEG HIVDIHDFSL GSSPHVRKHF PETWIWLDTN MGYRIYQEFE VTVPDSITSW VATGFVISED LGLGLTTTPV ELQAFQPFFI FLNLPYSVIR GEEFALEITI FNYLKDATEV KVIIEKSDKF DILMTSNEIN ATGHQQTLLV PSEDGATVLF PIRPTHLGEI PITVTALSPT ASDAVTQMIL VKAEGIEKSY SQSILLDLTD NRLQSTLKTL SFSFPPNTVT GSERVQITAI GDVLGPSING LASLIRMPYG CGEQNMINFA PNIYILDYLT KKKQLTDNLK EKALSFMRQG YQRELLYQRE DGSFSAFGNY DPSGSTWLSA FVLRCFLEAD PYIDIDQNVL HRTYTWLKGH QKSNGEFWDP GRVIHSELQG GNKSPVTLTA YIVTSLLGYR KYQPNIDVQE SIHFLESEFS RGISDNYTLA LITYALSSVG SPKAKEALNM LTWRAEQEGG MQFWVSSESK LSDSWQPRSL DIEVAAYALL SHFLQFQTSE GIPIMRWLSR QRNSLGGFAS TQDTTVALKA LSEFAALMNT ERTNIQVTVT GPSSPSPVKF LIDTHNRLLL QTAELAVVQP TAVNISANGF GFAICQLNVV YNVKASGSSR RRRSIQNQEA FDLDVAVKEN KDDLNHVDLN VCTSFSGPGR SGMALMEVNL LSGFMVPSEA ISLSETVKKV EYDHGKLNLY LDSVNETQFC VNIPAVRNFK VSNTQDASVS IVDYYEPRRQ AVRSYNSEVK LSSCDLCSDV QGCRPCEDGA SGSHHHSSVI FIFCFKLLYF MELWL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with CD109?

The strongest Open Targets associations for CD109 are heel bone mineral density, calcium measurement, CD109 antigen measurement, bone quantitative ultrasound measurement and bone density.

How long is the CD109 protein?

The Homo sapiens CD109 protein (UniProt Q6YHK3) is 1445 amino acids long.

Browse: Targets: C · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6YHK3
GeneCD109
OrganismHomo sapiens
Length1445
Binders0
Diseases283
View on UniProt