Gliomedin (GLDN)
Homo sapiens — UniProt Q6ZMI3
Data last refreshed: (UniProt release unknown)
Key facts
Gliomedin (GLDN) is a protein from Homo sapiens identified by UniProt accession Q6ZMI3, 551 residues long. MolForge cross-references it against 0 known binders and 109 disease associations.
- UniProt accession: Q6ZMI3; gene symbol GLDN.
- Organism: Homo sapiens.
- Length: 551 amino acids.
- Top disease associations (Open Targets): lethal congenital contracture syndrome, Polyhydramnios and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Gliomedin |
|---|---|
| UniProt accession | Q6ZMI3 |
| Gene | GLDN |
| Organism | Homo sapiens |
| Length | 551 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (109)
Diseases linked to this target (Open Targets).
- lethal congenital contracture syndrome · score 0.66
- Polyhydramnios · score 0.44
- heel bone mineral density · score 0.42
- vital capacity · score 0.40
- body height · score 0.38
- fetal akinesia deformation sequence · score 0.37
- fetal akinesia deformation sequence 1 · score 0.37
- arthrogryposis multiplex congenita · score 0.30
- bone quantitative ultrasound measurement · score 0.29
- Flexion contracture · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZMI3-F1 | alphafold | PREDICTED | 72.71 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZMI3.
Amino-acid sequence (551 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GLDN?
The strongest Open Targets associations for GLDN are lethal congenital contracture syndrome, Polyhydramnios, heel bone mineral density, vital capacity and body height.
How long is the GLDN protein?
The Homo sapiens GLDN protein (UniProt Q6ZMI3) is 551 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZMI3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZMI3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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