Serine/threonine-protein kinase LMTK1 (AATK)
Homo sapiens — UniProt Q6ZMQ8
Data last refreshed: (UniProt release unknown)
Key facts
Serine/threonine-protein kinase LMTK1 (AATK) is a protein from Homo sapiens identified by UniProt accession Q6ZMQ8, 1374 residues long. MolForge cross-references it against 0 known binders and 103 disease associations.
- UniProt accession: Q6ZMQ8; gene symbol AATK.
- Organism: Homo sapiens.
- Length: 1374 amino acids.
- Top disease associations (Open Targets): lean body mass, fat body mass and body mass index.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Serine/threonine-protein kinase LMTK1 |
|---|---|
| UniProt accession | Q6ZMQ8 |
| Gene | AATK |
| Organism | Homo sapiens |
| Length | 1374 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (103)
Diseases linked to this target (Open Targets).
- lean body mass · score 0.45
- fat body mass · score 0.42
- body mass index · score 0.37
- appendicular lean mass · score 0.37
- body fat percentage · score 0.36
- neuroticism measurement · score 0.36
- depressive symptom measurement · score 0.33
- neutrophil count · score 0.32
- wellbeing measurement · score 0.32
- IGF-1 measurement · score 0.31
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZMQ8-F1 | alphafold | PREDICTED | 47.36 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZMQ8.
Amino-acid sequence (1374 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with AATK?
The strongest Open Targets associations for AATK are lean body mass, fat body mass, body mass index, appendicular lean mass and body fat percentage.
How long is the AATK protein?
The Homo sapiens AATK protein (UniProt Q6ZMQ8) is 1374 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZMQ8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZMQ8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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