Lysine-specific demethylase 7A (KDM7A)
Homo sapiens — UniProt Q6ZMT4
Data last refreshed: (UniProt release unknown)
Key facts
Lysine-specific demethylase 7A (KDM7A) is a protein from Homo sapiens identified by UniProt accession Q6ZMT4, 941 residues long. MolForge cross-references it against 1 known binders and 64 disease associations.
- UniProt accession: Q6ZMT4; gene symbol KDM7A.
- Organism: Homo sapiens.
- Length: 941 amino acids.
- Top disease associations (Open Targets): cancer, body mass index and platelet count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysine-specific demethylase 7A |
|---|---|
| UniProt accession | Q6ZMT4 |
| Gene | KDM7A |
| Organism | Homo sapiens |
| Length | 941 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (64)
Diseases linked to this target (Open Targets).
- cancer · score 0.56
- body mass index · score 0.41
- platelet count · score 0.41
- platelet crit · score 0.39
- breast carcinoma · score 0.37
- body height · score 0.36
- FEV/FVC ratio · score 0.33
- brain measurement · score 0.29
- urate measurement · score 0.27
- breast adenocarcinoma · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZMT4-F1 | alphafold | PREDICTED | 66.14 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZMT4.
Amino-acid sequence (941 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KDM7A?
The strongest Open Targets associations for KDM7A are cancer, body mass index, platelet count, platelet crit and breast carcinoma.
How long is the KDM7A protein?
The Homo sapiens KDM7A protein (UniProt Q6ZMT4) is 941 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZMT4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZMT4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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