Protein LEKR1 (LEKR1)
Homo sapiens — UniProt Q6ZMV7
Data last refreshed: (UniProt release unknown)
Key facts
Protein LEKR1 (LEKR1) is a protein from Homo sapiens identified by UniProt accession Q6ZMV7, 132 residues long. MolForge cross-references it against 0 known binders and 78 disease associations.
- UniProt accession: Q6ZMV7; gene symbol LEKR1.
- Organism: Homo sapiens.
- Length: 132 amino acids.
- Top disease associations (Open Targets): heel bone mineral density, bone quantitative ultrasound measurement and bone density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein LEKR1 |
|---|---|
| UniProt accession | Q6ZMV7 |
| Gene | LEKR1 |
| Organism | Homo sapiens |
| Length | 132 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (78)
Diseases linked to this target (Open Targets).
- heel bone mineral density · score 0.35
- bone quantitative ultrasound measurement · score 0.33
- bone density · score 0.32
- cortical surface area measurement · score 0.18
- sunburn · score 0.18
- calcium measurement · score 0.18
- interleukin 18 measurement · score 0.18
- skin pigmentation · score 0.16
- body height · score 0.16
- forced expiratory volume · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZMV7-F1 | alphafold | PREDICTED | 92.64 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZMV7.
Amino-acid sequence (132 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LEKR1?
The strongest Open Targets associations for LEKR1 are heel bone mineral density, bone quantitative ultrasound measurement, bone density, cortical surface area measurement and sunburn.
How long is the LEKR1 protein?
The Homo sapiens LEKR1 protein (UniProt Q6ZMV7) is 132 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZMV7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZMV7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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