Kinesin-like protein KIF6 (KIF6)
Homo sapiens — UniProt Q6ZMV9
Data last refreshed: (UniProt release unknown)
Key facts
Kinesin-like protein KIF6 (KIF6) is a protein from Homo sapiens identified by UniProt accession Q6ZMV9, 814 residues long. MolForge cross-references it against 0 known binders and 119 disease associations.
- UniProt accession: Q6ZMV9; gene symbol KIF6.
- Organism: Homo sapiens.
- Length: 814 amino acids.
- Top disease associations (Open Targets): refractive error measurement, cup-to-disc ratio measurement and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Kinesin-like protein KIF6 |
|---|---|
| UniProt accession | Q6ZMV9 |
| Gene | KIF6 |
| Organism | Homo sapiens |
| Length | 814 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (119)
Diseases linked to this target (Open Targets).
- refractive error measurement · score 0.50
- cup-to-disc ratio measurement · score 0.41
- brain measurement · score 0.40
- cortical surface area measurement · score 0.39
- optic disc area measurement · score 0.33
- optic cup area measurement · score 0.33
- cortical thickness · score 0.33
- nose morphology measurement · score 0.32
- neuroimaging measurement · score 0.30
- facial morphology measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZMV9-F1 | alphafold | PREDICTED | 71.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZMV9.
Amino-acid sequence (814 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KIF6?
The strongest Open Targets associations for KIF6 are refractive error measurement, cup-to-disc ratio measurement, brain measurement, cortical surface area measurement and optic disc area measurement.
How long is the KIF6 protein?
The Homo sapiens KIF6 protein (UniProt Q6ZMV9) is 814 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZMV9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZMV9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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