WD repeat-containing protein 88 (WDR88)
Homo sapiens — UniProt Q6ZMY6
Data last refreshed: (UniProt release unknown)
Key facts
WD repeat-containing protein 88 (WDR88) is a protein from Homo sapiens identified by UniProt accession Q6ZMY6, 472 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q6ZMY6; gene symbol WDR88.
- Organism: Homo sapiens.
- Length: 472 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, heel bone mineral density and brain volume measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | WD repeat-containing protein 88 |
|---|---|
| UniProt accession | Q6ZMY6 |
| Gene | WDR88 |
| Organism | Homo sapiens |
| Length | 472 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.08
- heel bone mineral density · score 0.06
- brain volume measurement · score 0.04
- basophil percentage of granulocytes · score 0.03
- basophil percentage of leukocytes · score 0.03
- basophil count · score 0.03
- femoral neck bone mineral density · score 0.03
- velocity of sound measurement · score 0.03
- bone quantitative ultrasound measurement · score 0.03
- spine bone mineral density · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZMY6-F1 | alphafold | PREDICTED | 77.03 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZMY6.
Amino-acid sequence (472 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with WDR88?
The strongest Open Targets associations for WDR88 are mean corpuscular volume, heel bone mineral density, brain volume measurement, basophil percentage of granulocytes and basophil percentage of leukocytes.
How long is the WDR88 protein?
The Homo sapiens WDR88 protein (UniProt Q6ZMY6) is 472 amino acids long.
Browse: Targets: W · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZMY6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZMY6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.