Zinc finger protein 517 (ZNF517)
Homo sapiens — UniProt Q6ZMY9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 517 (ZNF517) is a protein from Homo sapiens identified by UniProt accession Q6ZMY9, 492 residues long. MolForge cross-references it against 0 known binders and 5 disease associations.
- UniProt accession: Q6ZMY9; gene symbol ZNF517.
- Organism: Homo sapiens.
- Length: 492 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, type 2 diabetes mellitus and COVID-19.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 517 |
|---|---|
| UniProt accession | Q6ZMY9 |
| Gene | ZNF517 |
| Organism | Homo sapiens |
| Length | 492 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (5)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.36
- type 2 diabetes mellitus · score 0.02
- COVID-19 · score 0.02
- adrenal cortex carcinoma · score 0.00
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZMY9-F1 | alphafold | PREDICTED | 67.81 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZMY9.
Amino-acid sequence (492 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF517?
The strongest Open Targets associations for ZNF517 are neurodegenerative disease, type 2 diabetes mellitus, COVID-19, adrenal cortex carcinoma and neoplasm.
How long is the ZNF517 protein?
The Homo sapiens ZNF517 protein (UniProt Q6ZMY9) is 492 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZMY9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZMY9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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