MEF2-activating motif and SAP domain-containing transcriptional regulator (MAMSTR)
Homo sapiens — UniProt Q6ZN01
Data last refreshed: (UniProt release unknown)
Key facts
MEF2-activating motif and SAP domain-containing transcriptional regulator (MAMSTR) is a protein from Homo sapiens identified by UniProt accession Q6ZN01, 415 residues long. MolForge cross-references it against 0 known binders and 131 disease associations.
- UniProt accession: Q6ZN01; gene symbol MAMSTR.
- Organism: Homo sapiens.
- Length: 415 amino acids.
- Top disease associations (Open Targets): glomerular filtration rate, reticulocyte count and low density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | MEF2-activating motif and SAP domain-containing transcriptional regulator |
|---|---|
| UniProt accession | Q6ZN01 |
| Gene | MAMSTR |
| Organism | Homo sapiens |
| Length | 415 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (131)
Diseases linked to this target (Open Targets).
- glomerular filtration rate · score 0.31
- reticulocyte count · score 0.29
- low density lipoprotein cholesterol measurement · score 0.29
- platelet count · score 0.28
- alcohol consumption measurement · score 0.28
- Hypercholesterolemia · score 0.25
- galectin-3 measurement · score 0.24
- lipoprotein A measurement · score 0.23
- fat intake measurement · score 0.23
- body height · score 0.23
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZN01-F1 | alphafold | PREDICTED | 57.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN01.
Amino-acid sequence (415 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MAMSTR?
The strongest Open Targets associations for MAMSTR are glomerular filtration rate, reticulocyte count, low density lipoprotein cholesterol measurement, platelet count and alcohol consumption measurement.
How long is the MAMSTR protein?
The Homo sapiens MAMSTR protein (UniProt Q6ZN01) is 415 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZN01 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZN01 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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