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RNA-binding protein MEX3B (MEX3B)

Homo sapiens — UniProt Q6ZN04

Gene: MEX3BHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

RNA-binding protein MEX3B (MEX3B) is a protein from Homo sapiens identified by UniProt accession Q6ZN04, 569 residues long. MolForge cross-references it against 0 known binders and 108 disease associations.

  • UniProt accession: Q6ZN04; gene symbol MEX3B.
  • Organism: Homo sapiens.
  • Length: 569 amino acids.
  • Top disease associations (Open Targets): neurodegenerative disease, mean corpuscular volume and erythrocyte count.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRNA-binding protein MEX3B
UniProt accessionQ6ZN04
GeneMEX3B
OrganismHomo sapiens
Length569 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (108)

Diseases linked to this target (Open Targets).

  • neurodegenerative disease · score 0.46
  • mean corpuscular volume · score 0.36
  • erythrocyte count · score 0.30
  • red blood cell density measurement · score 0.27
  • colorectal cancer · score 0.26
  • aspirin use measurement · score 0.26
  • drug use measurement · score 0.26
  • NSAID use measurement · score 0.26
  • Abnormality of refraction · score 0.25
  • sitting height measurement · score 0.22

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6ZN04-F1alphafoldPREDICTED61.42—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN04.

Amino-acid sequence (569 residues)

MPSSLFADLE RNGSGGGGGG SSGGGETLDD QRALQLALDQ LSLLGLDSDE GASLYDSEPR KKSVNMTECV PVPSSEHVAE IVGRQGCKIK ALRAKTNTYI KTPVRGEEPV FVVTGRKEDV AMARREIISA AEHFSMIRAS RNKNTALNGA VPGPPNLPGQ TTIQVRVPYR VVGLVVGPKG ATIKRIQQQT HTYIVTPSRD KEPVFEVTGM PENVDRAREE IEAHIALRTG GIIELTDEND FHANGTDVGF DLHHGSGGSG PGSLWSKPTP SITPTPGRKP FSSYRNDSSS SLGSASTDSY FGGGTSSSAA ATQRLADYSP PSPALSFAHN GNNNNNGNGY TYTAGGEASV PSPDGCPELQ PTFDPAPAPP PGAPLIWAQF ERSPGGGPAA PVSSSCSSSA SSSASSSSVV FPGGGASAPS NANLGLLVHR RLHPGTSCPR LSPPLHMAPG AGEHHLARRV RSDPGGGGLA YAAYANGLGA QLPGLQPSDT SGSSSSSSSS SSSSSSSSGL RRKGSRDCSV CFESEVIAAL VPCGHNLFCM ECANRICEKS EPECPVCHTA VTQAIRIFS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with MEX3B?

The strongest Open Targets associations for MEX3B are neurodegenerative disease, mean corpuscular volume, erythrocyte count, red blood cell density measurement and colorectal cancer.

How long is the MEX3B protein?

The Homo sapiens MEX3B protein (UniProt Q6ZN04) is 569 amino acids long.

Browse: Targets: M · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6ZN04
GeneMEX3B
OrganismHomo sapiens
Length569
Binders0
Diseases108
View on UniProt