Zinc finger protein 66 (ZNF66)
Homo sapiens — UniProt Q6ZN08
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 66 (ZNF66) is a protein from Homo sapiens identified by UniProt accession Q6ZN08, 573 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q6ZN08; gene symbol ZNF66.
- Organism: Homo sapiens.
- Length: 573 amino acids.
- Top disease associations (Open Targets): Sepsis, Down syndrome and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 66 |
|---|---|
| UniProt accession | Q6ZN08 |
| Gene | ZNF66 |
| Organism | Homo sapiens |
| Length | 573 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- Sepsis · score 0.01
- Down syndrome · score 0.01
- head and neck squamous cell carcinoma · score 0.00
- migraine disorder · score 0.00
- acute myeloid leukemia · score 0.00
- esophageal squamous cell carcinoma · score 0.00
- cancer · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6ZN08-F1 | alphafold | PREDICTED | 73.59 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6ZN08.
Amino-acid sequence (573 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF66?
The strongest Open Targets associations for ZNF66 are Sepsis, Down syndrome, head and neck squamous cell carcinoma, migraine disorder and acute myeloid leukemia.
How long is the ZNF66 protein?
The Homo sapiens ZNF66 protein (UniProt Q6ZN08) is 573 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6ZN08 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6ZN08 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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